Double-Drug attack shows promise against tough lung cancer

NCT ID NCT03392246

First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 27 times

Summary

This study tests whether combining two targeted drugs, osimertinib and selumetinib, can shrink tumors or slow disease in people with advanced EGFR-mutant non-small cell lung cancer who have not yet taken EGFR inhibitors. About 25 participants will receive the combination and be monitored with CT scans. The goal is to see how well the drugs work together and how long the benefits last.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02214, United States

Conditions

Explore the condition pages connected to this study.