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Major trial tests High-Dose weight loss pill: can a daily tablet shed pounds?

NCT ID NCT05035095

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

Summary

This study tested whether a higher dose of a daily oral medication (semaglutide 50 mg) could help adults with overweight or obesity lose weight. Over 660 participants were randomly assigned to take either the active pill or a placebo (dummy pill) for 68 weeks, alongside lifestyle counseling on diet and exercise. The main goal was to measure changes in body weight and see how many people achieved significant weight loss (5% or more of their body weight).

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accellacare

    Wilmington, North Carolina, 28401, United States

  • Capital Clin Res Ctr,LLC

    Olympia, Washington, 98502, United States

  • Center for Klinisk Metabolisk Forskning

    Hellerup, 2900, Denmark

  • Centre Hospitalier Universitaire de Bordeaux-Hopital Haut Leveque-2

    Pessac, 33600, France

  • Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1

    Saint-Herblain, 44800, France

  • Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-2

    Toulouse, 31054, France

  • Centre de Recherche Clinique Portes Du Sud

    Vénissieux, 69200, France

  • Centrum Medyczne Pratia Gdynia

    Gdynia, Pomeranian Voivodeship, 81-338, Poland

  • Centrum Terapii Wspolczesnej J.M. Jasnorzewska S.K.A.

    Lodz, 90-338, Poland

  • Centrum Zdrowia Metabolicznego

    Poznan, Wielkopolskie Voivodeship, 60-589, Poland

  • Chiba University Hospital_Diabetes, Metabolism and Endocrinology

    Chiba-shi, Chiba, 260-8677, Japan

  • Clinical Trial Res Assoc,Inc

    Plantation, Florida, 33324, United States

  • Diabetes Zentrum Wandsbek Berufsausuebungsgemeinschaft GbR

    Hamburg, 22041, Germany

  • East West Med Res Inst

    Honolulu, Hawaii, 96814, United States

  • Endocrinological Dispensary of Department of healthcare ser.

    Moscow, 119034, Russia

  • FSBI 'I.I. Dedov National Medical Research Center of Endocrinology' of the MH of Russia

    Moscow, 117292, Russia

  • Federal Bureau for Medical and Social Expertise

    Moscow, 127486, Russia

  • Fondation Hôtel-Dieu

    Le Creusot, 71200, France

  • G.A. Research Associates Ltd.

    Moncton, New Brunswick, E1G 1A7, Canada

  • Gabinet Leczenia Otylosci i Chorob Dietozaleznych

    Bialystok, Podlaskie Voivodeship, 15-281, Poland

  • Groupe Sos Sante-Hopital Le Creusot-Hotel Dieu-2

    Le Creusot, 71200, France

  • Higashi-shinjuku clinic

    Tokyo, 169-0072, Japan

  • Hvidovre Hospital Endokrinologisk forsknings afsnit 159

    Hvidovre, 2650, Denmark

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • Joint Stock Company "Medical technologies"

    Yekaterinburg, 620075, Russia

  • Joint Stock Company "Polyclinic Complex"

    Saint Petersburg, 190013, Russia

  • LLC "Clinic of new technologies in Medicine"

    Dzerzhinskiy, 140091, Russia

  • Leningrad Regional Clinical Hospital

    Saint Petersburg, 194291, Russia

  • Les Hopitaux de Chartres-Hopital Louis Pasteur

    Le Coudray, 28630, France

  • MZM Praxis Drs. Erlinger

    Stuttgart, 70378, Germany

  • Midwest Inst For Clin Res

    Indianapolis, Indiana, 46260, United States

  • Milek, Hohenmölsen

    Hohenmölsen, 06679, Germany

  • NZOZ Przychodnia Specjalistyczna Medica

    Lublin, Lubelski, 20-538, Poland

  • Nova Scotia Health Authority

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Obesity Research Unit

    Helsinki, 00014, Finland

  • Ocean West Research Clinic

    Surrey, British Columbia, V3Z 2N6, Canada

  • Praxis Dr. med. M. Esser

    Essen, 45219, Germany

  • Praxis Dr. med. Wenzl-Bauer

    Rehlingen-Siersburg, 66780, Germany

  • Premier Clinical Trial Research Network (PCTRN)

    Hamilton, Ontario, L8M 1K7, Canada

  • RED-Institut für medizinische Forschung und Fortbildung GmbH

    Oldenburg in Holstein, 23758, Germany

  • Rochester Clinical Research, Inc.

    Rochester, New York, 14609, United States

  • Seinäjoen keskussairaala

    Seinäjoki, 60220, Finland

  • Selma Medical Associates

    Winchester, Virginia, 22601-3834, United States

  • Sjællands Universitetshospital, Køge - Medicinsk Afdeling

    Køge, 4600, Denmark

  • Slagelse Sygehus Ambulatorium for hjertesygdomme

    Slagelse, 4200, Denmark

  • StudyCor

    Jyväskylä, 40620, Finland

  • Suidoubashi Medical Clinic

    Chiyoda-ku, Tokyo, 101-0065, Japan

  • The Chappel Group Research

    Kissimmee, Florida, 34744, United States

  • The University of Penn Center

    Philadelphia, Pennsylvania, 19104-3317, United States

  • Tumen State Medical University

    Tyumen, Russia, 625023, Russia

  • Univ of Alabama Birmingham

    Birmingham, Alabama, 35233, United States

  • Velocity Clin Res Los Angeles

    Los Angeles, California, 90017, United States

  • Velocity Clinical Res-Dallas

    Dallas, Texas, 75230, United States

  • Washington Cntr Weight Mgmt

    Arlington, Virginia, 22206, United States

  • Wharton Med Clin Trials

    Hamilton, Ontario, L8L 5G8, Canada

  • Zentrum für klinische Studien Allgäu Oberschwaben

    Wangen, 88239, Germany

Conditions

Explore the condition pages connected to this study.

OBESITY OVERWEIGHT