Heart surgery pain relief: pill vs IV shot tested

NCT ID NCT06720415

First seen Nov 01, 2025 · Last updated Apr 11, 2026 · Updated 21 times

Summary

This study compared two ways of giving methadone pain medication to patients having elective heart surgery. Researchers tested whether taking methadone as a pill before surgery works as well as getting it through an IV during anesthesia. The goal was to see which method provides better pain relief after surgery while reducing overall opioid use.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.