New semaglutide pill study: does water amount matter?
NCT ID NCT05996874
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new tablet version of semaglutide (the drug in Ozempic and Rybelsus) in 121 healthy men. Researchers wanted to see how different amounts of water (50 mL vs 120 mL) and different delays before breakfast (30, 60, or 120 minutes) affect drug levels in the blood. Participants took one tablet daily for 10 days. The goal is to find the best way to take the pill for consistent absorption.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- semaglutide
- What this could lead to
- If successful, this could help optimize how to take oral semaglutide for better absorption and effectiveness.
- What could go wrong
- This is an early-phase study in healthy people, not patients. Results may not apply to those with diabetes or other conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Profil Institut für Stoffwechselforschung GmbH
Neuss, 41460, Germany
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