Blood test could decide who needs more chemo after oral cancer treatment

NCT ID NCT07296250

First seen Jan 09, 2026 · Last updated Jun 23, 2026 · Updated 26 times

Summary

This trial is for people with oral cancer who have completed surgery and standard chemoradiation. Researchers will use a blood test to look for leftover cancer cells (circulating tumor cells). If the test is positive, patients will receive three months of low-dose oral chemotherapy, with the option to continue up to a year if the cells persist. The goal is to see if this personalized approach can improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Linkou Chang Gung Memorial Hospital

    RECRUITING

    Taoyuan City, 333423, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-dose oral chemotherapy

What this could lead to

If successful, this could provide a way to personalize post-treatment care for oral cancer patients, potentially improving survival by catching and treating remaining cancer cells early.

What could go wrong

This is a small, early-phase trial with only 100 participants, so results may not apply to all patients. The approach relies on a new test (circulating tumor cells) that is still being validated, and the benefit of extended chemotherapy is not yet proven.

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms lip and oral cavity carcinoma Mouth Neoplasms Neoplastic Cells, Circulating oral cavity squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.