New decision tool aims to reduce aggressive End-of-Life cancer care

NCT ID NCT04823377

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a special decision-making tool can help doctors and patients with advanced non-small cell lung cancer decide when to stop cancer treatments. The goal is to reduce the number of patients receiving chemotherapy or other treatments in their last days of life, which can be harsh and offer little benefit. The study compares usual care to a period where the tool is used, involving 364 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could provide a reliable way to help doctors and patients decide when to stop cancer treatments, potentially improving quality of life at the end of life.
What could go wrong
This is an observational-style study comparing two time periods, not a randomized trial, so results may be influenced by other changes over time. It does not test a new drug or treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HP Ambroise Paré

    Boulogne-Billancourt, 92100, France

  • AP-HP Bichat

    Paris, 75018, France

  • AP-HP Cochin

    Paris, 75014, France

  • AP-HP Tenon

    Paris, 75970, France

  • CGFL

    Dijon, 21000, France

  • CH Abbeville

    Abbeville, 80142, France

  • CH Henri Duffaut Avignon

    Avignon, 84000, France

  • CH Intercommunal de Créteil

    Créteil, 94000, France

  • CH Saint-Malo

    St-Malo, 35420, France

  • CH du Pays d'Aix

    Aix-en-Provence, 13616, France

  • CHD Vendée

    La Roche-sur-Yon, 85925, France

  • CHI de Compiègne-Noyon

    Compiègne, 60200, France

  • CHR Metz-Thionville - Hôpital de Mercy

    Ars-Laquenexy, France

  • CHRU Lille

    Lille, 59000, France

  • CHU Amiens - Hôpital Sud

    Amiens, 80054, France

  • CHU Angers

    Angers, 49933, France

  • CHU Grenoble Alpes

    Grenoble, 38043, France

  • CHU Sud Francilien

    Corbeil-Essonnes, 91100, France

  • Centre Léon Bérard

    Lyon, 69008, France

  • Clinique Tessier

    Valenciennes, 59300, France

  • Clinique des Cèdres

    Cornebarrieu, 31700, France

  • Hôpital Foch

    Suresnes, 92150, France

  • Institut Curie

    Paris, 75005, France

  • Institut Curie

    Saint-Cloud, 92210, France

  • Institut Sainte-Catherine

    Avignon, 84918, France

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