Eye test and blood markers could spot dangerous pregnancy condition earlier
NCT ID NCT06122220
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study looks at whether measuring the optic nerve sheath (the lining around the nerve connecting the eye to the brain) combined with blood tests for angiogenic factors can better diagnose severe pre-eclampsia in pregnant women. Pre-eclampsia is a serious condition that can harm both mother and baby. The researchers will measure these markers in 200 pregnant women between 24 and 40 weeks of pregnancy to see if they can predict complications like organ damage or poor fetal growth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Measurement of optic nerve sheath diameter and sFLT-1/PIGF index
- What this could lead to
- If successful, this approach could help doctors more accurately diagnose severe pre-eclampsia and predict complications, potentially improving outcomes for mothers and babies.
- What could go wrong
- This is an early-stage diagnostic study with 200 participants, so results may not apply to all pregnant women. The measurements may not be precise enough to change clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama
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