Blood test could help rheumatoid arthritis patients safely reduce medication
NCT ID NCT07678112
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study tests a new tool called OPTIBIO that uses blood markers and patient data to help doctors decide if it's safe to reduce biological therapy in rheumatoid arthritis patients who are in remission. About 184 adults with RA in stable remission will be randomly assigned to have their treatment decisions guided by the tool or by their usual doctor. The goal is to see if the tool can help more patients stay in remission while using less medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Predictive model (OPTIBIO) using blood biomarkers and clinical data
What this could lead to
If successful, this tool could help doctors safely reduce medication for rheumatoid arthritis patients in remission, lowering costs and side effects while maintaining disease control.
What could go wrong
The tool is still being tested in a relatively small trial. It may not accurately predict flares for all patients, and reducing medication always carries a risk of disease worsening.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Complejo Hospitalario Universitario de A Coruña
RECRUITINGA Coruña, A Coruña, 15006, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínico San Carlos
RECRUITINGMadrid, Madrid, 28040, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, Madrid, 28007, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Regional Universitario de Málaga
RECRUITINGMálaga, Málaga, 29010, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, Madrid, 28041, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Araba
RECRUITINGAlava, Alava, 01009, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario La Princesa
RECRUITINGMadrid, Madrid, 28006, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario de Canarias
RECRUITINGSan Cristóbal de La Laguna, Santa Cruz de Tenerife, 38320, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital del Mar
RECRUITINGBarcelona, Barcelona, 08003, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••