Blood test could help rheumatoid arthritis patients safely reduce medication

NCT ID NCT07678112

Recruiting now Disease control Sponsor: Francisco J. Blanco Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests a new tool called OPTIBIO that uses blood markers and patient data to help doctors decide if it's safe to reduce biological therapy in rheumatoid arthritis patients who are in remission. About 184 adults with RA in stable remission will be randomly assigned to have their treatment decisions guided by the tool or by their usual doctor. The goal is to see if the tool can help more patients stay in remission while using less medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Predictive model (OPTIBIO) using blood biomarkers and clinical data
What this could lead to: If successful, this tool could help doctors safely reduce medication for rheumatoid arthritis patients in remission, lowering costs and side effects while maintaining disease control.
What could go wrong: The tool is still being tested in a relatively small trial. It may not accurately predict flares for all patients, and reducing medication always carries a risk of disease worsening.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS (RA)

Contacts and locations

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Locations

Complejo Hospitalario Universitario de A Coruña
RECRUITING

A Coruña, A Coruña, 15006, Spain
Hospital Clínico San Carlos
RECRUITING

Madrid, Madrid, 28040, Spain
Hospital General Universitario Gregorio Marañón
RECRUITING

Madrid, Madrid, 28007, Spain
Hospital Regional Universitario de Málaga
RECRUITING

Málaga, Málaga, 29010, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Madrid, 28041, Spain
Hospital Universitario Araba
RECRUITING

Alava, Alava, 01009, Spain
Hospital Universitario La Princesa
RECRUITING

Madrid, Madrid, 28006, Spain
Hospital Universitario de Canarias
RECRUITING

San Cristóbal de La Laguna, Santa Cruz de Tenerife, 38320, Spain
Hospital del Mar
RECRUITING

Barcelona, Barcelona, 08003, Spain

Contact Email: •••••@•••••

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