Opioid blocker may reveal Brain's social secrets
NCT ID NCT05007561
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether blocking opioid receptors with naltrexone changes how people feel socially connected and how their brains respond to social cues. 210 healthy adults will take either naltrexone or a placebo for 7 days, report daily feelings, and undergo brain scans. The goal is to understand the role of opioids in social experiences, not to treat any condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naltrexone
What this could lead to
If successful, this could reveal how opioids influence social bonding, potentially guiding future treatments for social disconnection.
What could go wrong
This is a very early, small study in healthy people, not a treatment trial. Results may not apply to clinical populations or lead to therapies.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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San Diego State University
RECRUITINGSan Diego, California, 92120, United States
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