Opioid blocker may reveal Brain's social secrets
NCT ID NCT05007561
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether blocking opioid receptors with naltrexone changes how people feel socially connected and how their brains respond to social cues. 210 healthy adults will take either naltrexone or a placebo for 7 days, report daily feelings, and undergo brain scans. The goal is to understand the role of opioids in social experiences, not to treat any condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- naltrexone
- What this could lead to
- If successful, this could reveal how opioids influence social bonding, potentially guiding future treatments for social disconnection.
- What could go wrong
- This is a very early, small study in healthy people, not a treatment trial. Results may not apply to clinical populations or lead to therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
San Diego State University
RECRUITINGSan Diego, California, 92120, United States
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