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Caffeine's Muscle-Boosting power may fade with age

NCT ID NCT07711652

Knowledge-focused Sponsor: University of Alcala Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study investigates whether caffeine improves muscle strength and endurance differently in young adults (ages 18–35) compared to older adults (ages 55–80). Participants receive either caffeine or a placebo before performing upper- and lower-body exercises. The goal is to understand if age changes caffeine's ergogenic effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
caffeine (3 mg/kg) or placebo (maltodextrin)
What this could lead to
If it works, this could help tailor caffeine recommendations for older adults to improve exercise performance.
What could go wrong
This is a small, early-stage study with healthy volunteers, so results may not apply to less active or older adults with health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jan 2023

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between ≥18 and 35 years in young adults and ≥ 55 and 80 years in older adults. * Body mass index (BMI) lower than 25 kg/m². * Physically active subjects (≥150 min/week of moderate exercise). * Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise. * Participants capable of performing the tests. Exclusion Criteria: * History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism. * Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study. * Body mass index (BMI) ≥ 25 kg/m². * Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study. * Performing strenuous exercise within 48 hours prior to the tests.• Failing to replicate the same food intake on the two experimental days. * Consuming caffeine after 6 PM on the day prior to training or testing.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caffeine Placebo

Contacts and locations

Locations

  • Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

    Alcalá de Henares, Madrid, 28805, Spain

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