Opioid vaccine trial aims to block Drug's brain effects

NCT ID NCT04458545

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a vaccine that helps the body produce antibodies against oxycodone, a commonly abused prescription opioid. The goal is to reduce the drug's ability to reach the brain and lower its pleasurable effects. The trial involves 45 adults with opioid use disorder and focuses on safety, immune response, and drug liking. It is not a cure but a new tool to support ongoing treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinilabs Drug Development Corporation

    RECRUITING

    Eatontown, New Jersey, 07724, United States

  • New York State Psychiatric Institute: Division on Substance Use Disorders

    ACTIVE_NOT_RECRUITING

    New York, New York, 10032, United States

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Other studies related to the condition(s) this trial covers.