Spinal block may speed up chemo start after cancer surgery

NCT ID NCT07153614

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether using spinal morphine or other nerve blocks instead of standard opioid painkillers can help patients start chemotherapy sooner after cancer surgery. 200 adults having open surgery for stomach, liver, pancreas, or colorectal cancer will be randomly assigned to one of three pain-block methods. The main goal is to see if the spinal morphine group begins chemo earlier than the others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

intrathecal morphine, bupivacaine, dexamethasone, and Exparel-based solution

What this could lead to

If it works, this could show that using spinal morphine before surgery helps patients start chemotherapy sooner after cancer surgery.

What could go wrong

This is a small, early-stage study (200 people) comparing different pain-block methods. Results may not apply to all surgeries or patients, and pain blocks carry rare risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Tennessee Graduate School of Medicine

    RECRUITING

    Knoxville, Tennessee, 37920, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••