Native-Focused program aims to curb opioid use in young adults

NCT ID NCT04617938

Completed Prevention Sponsor: RAND Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tested a program called TACUNA plus Wellness Circle, designed to prevent opioid misuse among American Indian and Alaska Native young adults aged 18-25 in California. The program uses motivational interviewing and traditional practices in virtual workshops. Researchers compared it to a standard opioid education workshop over 12 months to see if it reduces drug use and strengthens healthy social networks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TACUNA plus Wellness Circle (behavioral intervention)
What this could lead to: If it works, this could provide a culturally tailored way to prevent opioid misuse and reduce substance use among urban AI/AN young adults.
What could go wrong: This is a completed study with 541 participants, but results are not yet widely confirmed. The intervention is behavioral, so effects may vary by individual and setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALCOHOL DRINKING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alcohol Drinking Marijuana Use opioid abuse opiate dependence prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL DRINKING MARIJUANA USE OPIOID USE

Contacts and locations

Locations

RAND Corporation

Santa Monica, California, 90401, United States
UCLA

Los Angeles, California, 90095, United States
United American Indian Involvement, Inc

Los Angeles, California, 90017, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.