Native-Focused program aims to curb opioid use in young adults

NCT ID NCT04617938

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a program called TACUNA plus Wellness Circle, designed to prevent opioid misuse among American Indian and Alaska Native young adults aged 18-25 in California. The program uses motivational interviewing and traditional practices in virtual workshops. Researchers compared it to a standard opioid education workshop over 12 months to see if it reduces drug use and strengthens healthy social networks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TACUNA plus Wellness Circle (behavioral intervention)

What this could lead to

If it works, this could provide a culturally tailored way to prevent opioid misuse and reduce substance use among urban AI/AN young adults.

What could go wrong

This is a completed study with 541 participants, but results are not yet widely confirmed. The intervention is behavioral, so effects may vary by individual and setting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID USE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alcohol Drinking Marijuana Use opioid abuse opiate dependence prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • RAND Corporation

    Santa Monica, California, 90401, United States

  • UCLA

    Los Angeles, California, 90095, United States

  • United American Indian Involvement, Inc

    Los Angeles, California, 90017, United States