New pill packaging aims to curb opioid overprescribing after surgery

NCT ID NCT04598074

Not yet recruiting Knowledge-focused Sponsor: UConn Health Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a special child-resistant blister pack with clear labeling can help reduce how many opioid pills are prescribed and used after orthopedic surgery. About 352 adults will receive either the new packaging or the standard orange bottle. Researchers will track the number of pills prescribed and used, and see if the new pack improves safety and reduces leftover medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Opioid Package Prototype (special blister pack)
What this could lead to: If it works, this could lead to safer opioid use after surgery by reducing the number of pills prescribed and leftover pills at home.
What could go wrong: This is an early feasibility study, not a large-scale trial. The packaging may not change prescribing habits or patient use as hoped, and results may not apply to other settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Blister opioid abuse Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID PRESCRIBING, DISPENSING, AND PATIENT USE OPIOID USE

Contacts and locations

Locations

UConn Health

Farmington, Connecticut, 06030, United States

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