Tiny study probes Marijuana-Opioid interaction
NCT ID NCT05485012
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study looked at how marijuana and an opioid drug influence each other's use in healthy adults aged 18-50 who had experience with both substances. Eight participants lived at a research unit for about 6.5 weeks and could earn doses of each drug under controlled conditions. The goal was to understand how these drugs interact, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Marijuana and an opioid (oxycodone-like drug)
- What this could lead to
- If successful, this could help researchers understand how these drugs interact, potentially guiding future treatments for substance use.
- What could go wrong
- This was a very small, early-phase study with only 8 people. It was not designed to test a treatment, so results may not apply broadly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Kentucky
Lexington, Kentucky, 40506, United States
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