Tiny study probes Marijuana-Opioid interaction
NCT ID NCT05485012
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study looked at how marijuana and an opioid drug influence each other's use in healthy adults aged 18-50 who had experience with both substances. Eight participants lived at a research unit for about 6.5 weeks and could earn doses of each drug under controlled conditions. The goal was to understand how these drugs interact, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Marijuana and an opioid (oxycodone-like drug)
What this could lead to
If successful, this could help researchers understand how these drugs interact, potentially guiding future treatments for substance use.
What could go wrong
This was a very small, early-phase study with only 8 people. It was not designed to test a treatment, so results may not apply broadly.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Kentucky
Lexington, Kentucky, 40506, United States