No-Opioid anesthesia may ease stress of major aneurysm surgery

This study compares opioid-free anesthesia to standard opioid-based anesthesia in 40 adults undergoing open abdominal aortic aneurysm repair. The goal is to see if avoiding opioids reduces the body's stress response and inflammation during and after surgery. Researchers will measure blood markers and pain levels to determine if the opioid-free approach is safer and equally effective.