Opioid breathing risks during sleep under the microscope
NCT ID NCT06854211
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will give a single dose of morphine or a placebo to 26 adults (some healthy, some with obstructive sleep apnea) during a sleep study night. Researchers will measure how much their breathing changes. The goal is to understand why opioids can dangerously slow breathing during sleep, especially in people with sleep apnea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Morphine
What this could lead to
If successful, this study could help explain why opioids sometimes cause dangerous breathing problems during sleep, potentially leading to safer pain management guidelines.
What could go wrong
This is a very small, early-phase study (26 people) that only looks at breathing changes, not long-term safety or outcomes. Results may not apply to everyone.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBSTRUCTIVE SLEEP APNEA (OSA) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••