Mind over MS: could online therapy lift the fog of depression?

NCT ID NCT07742579

Not yet recruiting Symptom relief Sponsor: Robert Simpson Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study tests whether an online mindfulness-based cognitive therapy (MBCT) program can reduce depression in people with multiple sclerosis (MS) who also have mild to moderate depression. The program involves live group sessions over eight weeks. Researchers will compare changes in depression, fatigue, sleep, pain, and quality of life between those who receive the therapy and those on a waiting list. They will also interview participants to understand their experiences and how the therapy could be improved.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Online group Mindfulness-Based Cognitive Therapy (MBCT) delivered live in weekly sessions for 8 weeks
What this could lead to: If effective, this online therapy could offer a practical, accessible way to help people with MS manage depression and improve quality of life.
What could go wrong: The trial is still in progress, and results may not show a clear benefit. Depression is complex, and what works for one person may not work for another.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

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