New hope for kids with devastating brain cancer in early drug trial

NCT ID NCT04732065

First seen Mar 09, 2026 · Last updated Apr 10, 2026 · Updated 5 times

Summary

This early-stage study is testing a new oral drug called ONC206, given alone or with radiation therapy, in children and young adults with aggressive brain tumors that have come back or are newly diagnosed. The main goals are to find the safest dose and see how the drug behaves in the body. Researchers also want to learn if the drug reaches the tumor and causes the cancer cells to die.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Email: •••••@•••••

  • Princess Máxima Center for Pediatric Oncology

    RECRUITING

    Utrecht, 3584, Netherlands

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

    Contact

  • The University Children's Hospital in Zurich

    RECRUITING

    Zurich, Canton of Zurich, 8032, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.