Sabine Mueller, Md, Phd

This study tests a combination of two drugs, gemcitabine and paxalisib, in children, teens, and young adults whose atypical teratoid rhabdoid tumor (ATRT) has come back or gotten worse. The goal is to find a safe dose and see if the drugs can control the tumor. About 29 participa…

This early-phase trial tests a new drug called ONC206 in children and young adults with diffuse midline glioma or other recurrent brain tumors. The drug aims to kill cancer cells by causing stress in them, without harming healthy cells. Researchers are looking for the safest dose…

This study is testing a drug called Tovorafenib for children and young adults with craniopharyngioma, a rare, non-cancerous brain tumor that can cause serious health problems. The drug is taken by mouth and works by blocking a protein that helps the tumor grow. The trial aims to …