First human trial launches for drug aimed at stopping colon cancer before it starts

NCT ID NCT05630794

Summary

This early-stage study is testing a drug called ONC201 (dordaviprone) to see if it is safe and can help prevent colorectal cancer. It is for adults who have a high risk of developing colon cancer due to a condition called Familial Adenomatous Polyposis (FAP) or a history of many colon polyps. Participants will take the drug as a weekly pill for 13 weeks while doctors closely monitor their health and check for changes in their colon tissue.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rhode Island Hospital

    NOT_YET_RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan Rogel Cancer Center

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.