Can Omega-3s in IV food help gut failure patients?

NCT ID NCT03869957

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding omega-3 fatty acids to intravenous (IV) nutrition could reduce oxidative stress in 20 adults with intestinal failure, a condition where the gut cannot absorb enough nutrients. Participants received either standard IV nutrition or IV nutrition with omega-3s for 7 days. The main goal was to see changes in a blood marker of cell damage. This small, early trial aims to gather initial data on a potential way to improve care for people who rely on IV feeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
omega-3 polyunsaturated fatty acids (n-3 PUFAs) given intravenously
What this could lead to
If it works, this could point toward a way to reduce oxidative stress and improve nutrition for people with intestinal failure.
What could go wrong
This is a very small, early study with only 20 participants. It only measured short-term markers, not long-term health outcomes, so results may not lead to a proven treatment.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

    Mexico City, Tlalpan, 14080, Mexico

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