New hope for kids with tough brain cancers: targeted radiation shows promise

NCT ID NCT04743661

First seen Feb 05, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This study tests a new treatment for children whose medulloblastoma or ependymoma has come back. It combines a specially designed antibody that delivers radiation directly into the brain fluid with standard chemotherapy drugs. The goal is to see if this approach can help children live longer without the cancer growing, and to check if it's feasible for ependymoma patients. About 62 children will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.