Could olive juice compounds help shield the aging brain?
NCT ID NCT07672938
First seen Jun 29, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study investigates whether a supplement made from hydroxytyrosol-rich olive juice, combined with a Mediterranean diet, can help prevent cognitive decline in people with mild cognitive impairment (MCI). Participants aged 50 to 85 with MCI will receive either a low or high dose of the supplement or a placebo, along with diet support, for 52 weeks. The goal is to see if this natural approach can slow memory and thinking problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hydroxytyrosol-rich olive juice polyphenol supplement
What this could lead to
If it works, this could point toward a simple dietary approach to slow or prevent memory loss in people with early cognitive problems.
What could go wrong
This is a small, early-stage trial with 141 participants, so results may not apply to everyone. The supplement may show no benefit over placebo, and long-term effects are unknown.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Palliative Care Centre "Panagia Glykofilousa", Greek Association of Alzheimer's Disease and Related Disorders, Plastira 65, Thessaloniki 54250, Greece.
RECRUITINGThessaloniki, Central Macedonia, 54250, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••