Could olive juice compounds help shield the aging brain?
NCT ID NCT07672938
First seen Jun 29, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study investigates whether a supplement made from hydroxytyrosol-rich olive juice, combined with a Mediterranean diet, can help prevent cognitive decline in people with mild cognitive impairment (MCI). Participants aged 50 to 85 with MCI will receive either a low or high dose of the supplement or a placebo, along with diet support, for 52 weeks. The goal is to see if this natural approach can slow memory and thinking problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hydroxytyrosol-rich olive juice polyphenol supplement
- What this could lead to
- If it works, this could point toward a simple dietary approach to slow or prevent memory loss in people with early cognitive problems.
- What could go wrong
- This is a small, early-stage trial with 141 participants, so results may not apply to everyone. The supplement may show no benefit over placebo, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Palliative Care Centre "Panagia Glykofilousa", Greek Association of Alzheimer's Disease and Related Disorders, Plastira 65, Thessaloniki 54250, Greece.
RECRUITINGThessaloniki, Central Macedonia, 54250, Greece
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