New painkiller aims to prevent gut woes after brain surgery

NCT ID NCT07650812

Not yet recruiting Symptom relief Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a drug called oliceridine can reduce stomach and bowel problems after brain surgery. About 176 adults having brain tumor removal will receive either oliceridine or a standard opioid during surgery. The goal is to see if oliceridine lowers the risk of nausea, vomiting, and constipation, which can be dangerous after neurosurgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oliceridine
What this could lead to: If it works, this could offer a way to reduce nausea, vomiting, and constipation after brain surgery, potentially lowering the risk of bleeding.
What could go wrong: This is a small, early-stage trial that hasn't started yet. The benefit over standard opioids is unproven, and oliceridine may still cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL DYSFUNCTION

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