New combo therapy tested for hard-to-treat breast cancer

NCT ID NCT03742245

First seen Dec 17, 2025 · Last updated May 24, 2026 · Updated 24 times

Summary

This early-stage trial tests the safety of combining two drugs, olaparib and vorinostat, in people with advanced breast cancer that has returned or spread. The study includes 28 adults whose cancer is not HER2-positive. The goal is to find the best dose and check for side effects, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.