New drug duo targets tough breast cancer in early trial

NCT ID NCT03641755

First seen Dec 12, 2025 · Last updated Apr 24, 2026 · Updated 17 times

Summary

This study tests a combination of two drugs, olaparib and sapacitabine, in people with advanced breast cancer that has a BRCA gene mutation. The main goals are to find the safest dose and see if the drugs shrink tumors. About 10 participants are enrolled in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Broad Institute of MIT

    Cambridge, Massachusetts, 02142, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.