New drug combo shows promise for inherited breast cancer

NCT ID NCT03641755

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a combination of two drugs, olaparib and sapacitabine, in people with breast cancer that has spread and who have a BRCA gene mutation. The main goals are to find the safest dose and see if the combination shrinks tumors. About 10 participants are enrolled.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Broad Institute of MIT

    Cambridge, Massachusetts, 02142, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.