New dosing strategy for schizophrenia drug aims to cut side effects

NCT ID NCT06821945

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests different ways to start taking olanzapine, a common schizophrenia medication, to see if a slower dose increase can reduce side effects while still controlling symptoms. About 120 adults with schizophrenia will receive one of several dosing schedules or a placebo. The goal is to find a safer, effective starting plan.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Olanzapine

What this could lead to

If successful, this could lead to a safer way to start olanzapine treatment for schizophrenia, reducing side effects while still controlling symptoms.

What could go wrong

This is an early phase 2 trial with only 120 participants, so results may not apply to everyone. Different dosing schedules may not improve safety or effectiveness as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hanyang University Guri Hospital

    NOT_YET_RECRUITING

    Guri-si, South Korea

    Contact

  • Kyungbook National university hospital

    RECRUITING

    Daegu, South Korea

    Contact