Long-Term study aims to unlock secrets of brittle bone disease
NCT ID NCT00001594
First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 5 times
Summary
This study followed 88 children and young adults with types III and IV osteogenesis imperfecta (brittle bone disease) to track how the condition changes over time. Researchers measured bone density, lung and heart function, hearing, and movement abilities. The goal was to better understand the disease's natural history and improve monitoring and care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better predict and manage complications of osteogenesis imperfecta, improving care and quality of life.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any new therapy, so it cannot lead to a cure or immediate treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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