Swallow a capsule, detect esophagus disease?
NCT ID NCT02422433
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a special imaging capsule (OFDI) that patients swallow to take detailed pictures of the esophagus. The goal is to see if it can accurately detect Barrett's esophagus, a condition that can lead to cancer. Researchers will compare the capsule's images with standard endoscopy and biopsy results in 130 adults already scheduled for an upper endoscopy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
OFDI capsule (imaging device)
What this could lead to
If successful, this could offer a less invasive way to detect and monitor Barrett's esophagus, potentially reducing the need for traditional endoscopy.
What could go wrong
This is an early feasibility study, not a treatment trial. The device may not be accurate enough to replace standard endoscopy, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Massachusetts General hospital
Boston, Massachusetts, 02114, United States