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New obesity drug shows promise in major japanese trial

NCT ID NCT06987695

Ongoing Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called maridebart cafraglutide to help adults in Japan with obesity lose weight. About 279 participants will receive either the drug or a placebo for 72 weeks. The main goals are to see how much weight they lose and if at least 5% of body weight is lost. This is a phase 3 trial, meaning it is in the final stage before possible approval.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Body Weight obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY DISEASE

Contacts and locations

Locations

  • Adachi Kyosai Hospital

    Adachi-ku, Tokyo, 120-0022, Japan

  • Aira Diabetes Thyroid Internal Medicine Clinic

    Aira-shi, Kagoshima-ken, 899-5421, Japan

  • Deguchi Clinic

    Kobe, Hyōgo, 652-0803, Japan

  • Fukuoka Shinmizumaki Hospital

    Onga-gun, Fukuoka, 807-0051, Japan

  • Hosokawa Surgical Clinic

    Nagoya, Aichi-ken, 453-0812, Japan

  • Ikebukuro Metropolitan Clinic

    Toshima-ku, Tokyo, 171-0021, Japan

  • Joh Medical Clinic

    Osaka, Osaka, 530-0002, Japan

  • Kobe University Hospital

    Kobe, Hyōgo, 650-0017, Japan

  • Kyoto University Hospital

    Kyoto, Kyoto, 606-8507, Japan

  • Kyushu University Hospital

    Fukuoka, Fukuoka, 812-8582, Japan

  • MIH Clinic Yoyogi

    Shibuya-ku, Tokyo, 151-0051, Japan

  • Manda Memorial Hospital

    Sapporo, Hokkaido, 060-0062, Japan

  • Matsuba Clinic

    Kawasaki-shi, Kanagawa, 212-0024, Japan

  • Matsunami Health Promotion Clinic

    Hashima-gun, Gifu, 501-6061, Japan

  • Medical Corporation Boocs Boocs Clinic Fukuoka

    Fukuoka, Fukuoka, 812-0025, Japan

  • Medical Corporation Chiseikai Tokyo Center Clinic

    Chuo-ku, Tokyo, 103-0027, Japan

  • Medical Corporation Keiseikai Kajiyama Clinic

    Kyoto, Kyoto, 600-8898, Japan

  • Medical Corporation Kenshinkai Minamino Cardiovascular Hospital

    Hachioji-shi, Tokyo, 192-0918, Japan

  • Meitetsu Hospital

    Nagoya, Aichi-ken, 451-8511, Japan

  • Midori Clinic

    Nagasaki, Nagasaki, 852-8034, Japan

  • Nihonbashi Sakura Clinic

    Chuo-ku, Tokyo, 103-0025, Japan

  • Nishiyamado Keiwa Hospital

    Naka, Ibaraki, 311-0133, Japan

  • Shimamura Memorial Hospital

    Nerima-ku, Tokyo, 177-0051, Japan

  • Shinjuku Southern Clinic

    Shinjuku-ku, Tokyo, 160-0023, Japan

  • Social Medical Corporation Kojunkai Daido Clinic

    Nagoya, Aichi-ken, 457-8511, Japan

  • Tashiro Endocrinology Clinic

    Fukuoka, Fukuoka, 814-0153, Japan

  • Tokyo Saiseikai Central Hospital

    Minato-ku, Tokyo, 108-0073, Japan

  • Urasoe General Hospital

    Urasoe-shi, Okinawa, 901-2102, Japan

  • Wellness Tenjin Clinic

    Fukuoka, Fukuoka, 810-0001, Japan

  • Yamasaki Family Clinic

    Amagasaki-shi, Hyōgo, 660-0861, Japan