Could nurses replace doctors for TB treatment? major trial underway
NCT ID NCT05671718
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study compares nurse-led treatment for drug-resistant tuberculosis (TB) in local clinics to standard doctor-led care in hospitals. About 2,944 people will take part across South Africa. The goal is to see if nurse-led care works just as well, is safe, and lowers costs for patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Doris Goodwin Hospital
RECRUITINGPietermaritzburg, KwaZulu-Natal, 3201, South Africa
Contact
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Jose Pearson Hospital
RECRUITINGPort Elizabeth, South Africa
Contact
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King Dinuzulu TB Hospital
RECRUITINGEast London, South Africa
Contact
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Murchison Hospital
RECRUITINGPort Shepstone, KwaZulu-Natal, 7007, South Africa
Contact
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Nkquebela TB Hospital
RECRUITINGEast London, South Africa
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nurse-led treatment (care delivery model)
What this could lead to
If successful, this could make drug-resistant TB treatment more accessible and affordable by shifting care from hospitals to local clinics.
What could go wrong
This is a large trial but still early in testing a new care model. Results may vary by location, and nurse-led care might not match hospital safety or outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.