Nurse support boosts TB treatment in south africa

NCT ID NCT02129244

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether having a nurse case manager helps people with multidrug-resistant tuberculosis (MDR-TB) and HIV complete their long treatment. About 3,600 patients in South Africa are involved. Half of the clinics have a nurse case manager to guide care, while the other half follow standard procedures. Researchers will compare treatment success rates between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nurse case management

What this could lead to

If successful, this approach could improve cure rates for drug-resistant TB, especially in patients also living with HIV.

What could go wrong

This is an observational study comparing existing care models, not testing a new drug. Results may vary by location and patient adherence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease multidrug-resistant tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Catherine Booth Hospital

    aMatikulu, KwaZulu-Natal, South Africa

  • Don McKenzie

    Durban, South Africa

  • Doris Goodwin Hospital

    Pietermaritzburg, South Africa

  • Dunstan Farrell Hospital

    Hibberdene, South Africa

  • Fort Gray Hospital

    East London, South Africa

  • Fosa Hospital

    Newlands West, South Africa

  • Hlabisa Hospital

    Hlabisa, South Africa

  • Jose Pearson Hospital

    Port Elizabeth, South Africa

  • King George V Hospital

    Durban, South Africa

  • Manguzi

    Manguzi, South Africa

  • Marjorie Parrish Hospital

    Port Alfred, South Africa

  • Murchison Hospital

    Port Shepstone, South Africa

  • Nkqubela

    Mdantsane, South Africa

  • Regus Primary Office

    Westville, Durban, 3629, South Africa

  • St Margaret's MDR-TB Hopsital

    Umzimkulu, South Africa