Radioactive injection takes on tough pancreatic cancer in early trial

NCT ID NCT06278454

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests a new radioactive drug called NRT6008, given alongside standard chemotherapy, for people with advanced pancreatic cancer that cannot be removed by surgery or has spread to nearby lymph nodes. The trial will enroll 58 adults to find the safest dose and check for side effects, while also watching for signs that tumors shrink. It is too early to know if this approach will work better than current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NRT6008 injection (a radioactive drug) plus standard chemotherapy (gemcitabine/nab-paclitaxel or FOLFIRINOX)

What this could lead to

If successful, this could lead to a new treatment option that shrinks tumors or slows progression in people with advanced pancreatic cancer that cannot be removed by surgery.

What could go wrong

This is a very early Phase I trial with only 58 participants, so the main goal is safety and finding the right dose—not yet proving it works. The radioactive drug may cause side effects like fatigue or damage to nearby organs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma Lymphatic Metastasis malignant pancreatic neoplasm metastatic malignant neoplasm in the lymph nodes pancreatic adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, China

    Contact

    Contact

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, China

    Contact

    Contact

  • Second Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, China

    Contact

    Contact

  • Shanghai Changhai Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

    Contact

    Contact

    Contact

  • Shanghai General Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

    Contact

    Contact

    Contact

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, China

    Contact

    Contact