New radiation 'Smart Bomb' targets Hard-to-Treat cancers in early trial

NCT ID NCT07660055

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new type of radiation therapy that seeks out and attacks cancer cells while sparing healthy tissue. It's for people with advanced breast, lung, stomach, or bladder cancer who have run out of standard options. The study will check if the treatment is safe, what dose works best, and whether it can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radioligand therapy (177Lu-DWJ155) and imaging agent (68Ga-DWJ155)

What this could lead to

If successful, this could lead to a new targeted treatment option for several hard-to-treat solid tumors.

What could go wrong

This is an early Phase 1 trial, so safety and dosing are still being figured out. It may not shrink tumors or work for all cancer types tested.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm gastric cancer gastroesophageal cancer gastroesophageal junction adenocarcinoma HER2 positive breast carcinoma hormone receptor-positive breast cancer neoplasm non-small cell lung carcinoma triple-negative breast carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Novartis Investigative Site

    RECRUITING

    Darlinghurst, New South Wales, 2010, Australia

  • Novartis Investigative Site

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Novartis Investigative Site

    RECRUITING

    Kashiwa, Chiba, 277-8577, Japan