New Non-Opioid drug could cut painkiller use after knee surgery

This study tests whether a non-opioid pain medicine called suzetrigine can reduce the need for opioid painkillers after total knee replacement surgery. About 210 adults will take either suzetrigine or a placebo for 14 days after surgery, and report their pain levels. The goal is to see if suzetrigine helps control pain and improves recovery without the risks of opioids.