Needle-Free myeloma monitoring: blood test and MRI show promise
NCT ID NCT05625971
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explored whether a simple blood test (liquid biopsy) and a whole-body MRI can detect leftover cancer cells in people with multiple myeloma, potentially replacing the need for a bone marrow biopsy. Researchers enrolled 36 adults with newly diagnosed or previously treated myeloma. The goal was to see how accurate these non-invasive methods are at finding minimal residual disease (MRD). If proven effective, this approach could make monitoring the disease much easier and less painful for patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a less invasive way to monitor multiple myeloma, potentially reducing the need for painful bone marrow biopsies.
What could go wrong
This is a small, completed study (36 people) focused on accuracy, not treatment. The methods may not be sensitive enough to replace biopsies in all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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New York Presbyterian Hospital/Columbia University Irving Medical Center
New York, New York, 10032, United States