New imaging tracer could spot kidney cancer without a needle
NCT ID NCT06090331
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This program gives patients with kidney masses access to a radioactive tracer called 89Zr-DFO-girentuximab, which is used with a PET/CT scan to detect clear cell renal cell carcinoma (a common kidney cancer) without surgery. The tracer attaches to a protein (CAIX) often found on these cancer cells, making them visible on the scan. The goal is to provide a non-invasive diagnostic option for patients who have suspicious kidney masses seen on standard CT or MRI.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
89Zr-DFO-girentuximab (a radioactive tracer for PET/CT imaging)
What this could lead to
If successful, this imaging method could provide a non-invasive way to detect clear cell renal cell carcinoma, potentially reducing the need for biopsies.
What could go wrong
This is an expanded access program, not a formal trial, so data on effectiveness and safety are limited. The tracer may not accurately distinguish all cancer types, and radiation exposure is a risk.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arkansas Urology
Little Rock, Arkansas, 72211, United States
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Austin Radiological Association
Austin, Texas, 78705, United States
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Biogenix Molecular
Miami, Florida, 33165, United States
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Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Indiana University
Bloomington, Indiana, 47405, United States
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Kansas University Medical Center
Kansas City, Kansas, 66103, United States
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Kettering Health Main Campus
Kettering, Ohio, 45429, United States
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M Health Fairview/ University of Minnesota
Minneapolis, Minnesota, 55455, United States
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MD Anderson Cancer Center
Houston, Texas, 77054, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Munson Medical Center
Traverse City, Michigan, 49684, United States
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Sarasota Memorial Health Care System
Sarasota, Florida, 34243, United States
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Stanford Urologic Cancer Program
Palo Alto, California, 94304, United States
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UCLA
Los Angeles, California, 90095, United States
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UT Southwestern
Dallas, Texas, 75390, United States
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United Theranostics
Glen Burnie, Maryland, 21061, United States
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Florida College of Medicine Jacksonville
Jacksonville, Florida, 32209, United States
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Urology Associates, PC
Nashville, Tennessee, 37209, United States
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Urology San Antonio
San Antonio, Texas, 78229, United States
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Xcancer
Omaha, Nebraska, 68130, United States