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Brain training vs. Alzheimer's: does it work?

NCT ID NCT00646269

Completed Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three non-drug approaches—cognitive training, reminiscence therapy, and a personalized program—in 640 people with mild-to-moderate Alzheimer's. The goal was to see if these therapies could delay progression to severe dementia. Participants were followed for changes in thinking, daily function, mood, and quality of life.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE

Contacts and locations

Locations

  • Association AA83 Alzheimer Aidants Var Etablissement " Les pensées "

    La Seyne-sur-Mer, 83500, France

  • Bagatelle

    Talence, 33401, France

  • CH Agen

    Agen, 47923, France

  • CHI Poissy-saint-germain-en-laye

    Poissy, 78300, France

  • CHIC Marmande - Tonneins

    Tonneins, 47400, France

  • CHRU de Saint-Etienne

    Saint-Etienne, 42055, France

  • CHU Amiens Nord

    Amiens, 80054, France

  • CHU Côte de Nacre

    Caen, 14033, France

  • CHU Limoges

    Limoges, 87042, France

  • CHU Purpan-Casselardit

    Toulouse, 31300, France

  • CHU de Rennes

    Rennes, 35000, France

  • CMRR & Neuropsychologie, Pavillon de Neurologie, CHU de Grenoble

    Grenoble, 38043, France

  • Centre Antonin Balmes

    Montpellier, 34295, France

  • Centre Hospitalier Bretagne Sud

    Lorient, 56322, France

  • Centre Hospitalier La Rochelle

    La Rochelle, 17000, France

  • Centre Hospitalier de Libourne

    Libourne, 33505, France

  • Centre Hospitalier des Pyrénées

    Pau, 64000, France

  • Centre Mémoire de Ressources et de Recherches de Bordeaux, CHU de Bordeaux

    Bordeaux, 33076, France

  • Centre Mémoire, Hôpital Pasteur,

    Nice, 06002, France

  • Centre de Gériatrie

    Dax, 40107, France

  • Centre hospitalier Ariège Couserans

    Saint-Girons, 09201, France

  • Centre pour Personnes Agées

    Colmar, 68020, France

  • Clinique Neurologique, CHU Nord

    Nantes, 44093, France

  • Groupe Hospitalier Saint-Augustin

    Malestroit, 56140, France

  • Hôpital Broca

    Paris, 75013, France

  • Hôpital Dupuytren

    Draveil, 92210, France

  • Hôpital Gui de Chauliac

    Montpellier, 34295, France

  • Hôpital Pellegrin

    Bordeaux, 33076, France

  • Hôpital Privé Gériatrique Les Magnolias

    Longjumeau, 91161, France

  • Hôpital Sainte-Marguerite

    Marseille, 13009, France

  • Hôpital Xavier-Arnozan

    Pessac, 33604, France

  • Hôpital de Jour Gériatrique

    Pau, 64000, France

  • Hôpital de Jour Gériatrique

    Saint-Raphaël, 83700, France

  • Hôpital de Jour gériatrique

    Poitiers, 86021, France

  • Hôpital de la Salpétrière,

    Paris, 75013, France

  • Hôpital des Charpennes

    Villeurbanne, 69100, France

  • Hôpitaux universitaires de Strasbourg

    Strasbourg, 67091, France

  • Les Fontaines de Monjous

    Gradignan, 33170, France

  • Pôle de Gérontologie CHICAS

    Gap, 05007, France

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