Immune cell therapy takes on autoimmune diseases

NCT ID NCT06733935

Recruiting now Disease control Sponsor: Nkarta, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment called NKX019 for people with autoimmune diseases like systemic sclerosis, rheumatoid arthritis, and vasculitis. NKX019 uses specially engineered immune cells to target and calm overactive B cells that cause the disease. The goal is to see if it is safe and can reduce symptoms, though ongoing management may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy anti-neutrophil cytoplasmic antibody-associated vasculitis diffuse scleroderma myositis disease rheumatoid arthritis systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIS IDIOPATHIC INFLAMMATORY MYOPATHIES RHEUMATOID ARTHRITIS SYSTEMIC SCLEROSIS

Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••

Locations

Nkarta Investigational Site
RECRUITING

Orange, California, 92868, United States

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Nkarta Investigational Site
RECRUITING

Gainesville, Florida, 32601, United States

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Nkarta Investigational Site
WITHDRAWN

Miami, Florida, 33133, United States
Nkarta Investigational Site
RECRUITING

Plantation, Florida, 33317, United States

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Nkarta Investigational Site
RECRUITING

Chicago, Illinois, 60612, United States

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Nkarta Investigational Site
RECRUITING

Fairway, Kansas, 66205, United States

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Nkarta Investigational Site
RECRUITING

Ann Arbor, Michigan, 48109, United States

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Nkarta Investigational Site
RECRUITING

Minneapolis, Minnesota, 55455, United States

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Nkarta Investigational Site
RECRUITING

Hackensack, New Jersey, 07601, United States

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Nkarta Investigational Site
RECRUITING

Summit, New Jersey, 07302, United States

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Nkarta Investigational Site
RECRUITING

New York, New York, 10007, United States

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Nkarta Investigational Site
RECRUITING

Stony Brook, New York, 11794, United States

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Nkarta Investigational Site
RECRUITING

Syracuse, New York, 13202, United States

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Nkarta Investigational Site
RECRUITING

Dallas, Texas, 75201, United States

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Nkarta Investigational Site
RECRUITING

Houston, Texas, 77002, United States

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Nkarta Investigational Site
RECRUITING

Melbourne, Victoria, 3000, Australia

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Nkarta Investigational Site
RECRUITING

Manati, 00674, Puerto Rico

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