Immune cell therapy takes on lupus kidney disease

NCT ID NCT06557265

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests a new treatment called NKX019, which uses specially engineered immune cells (CAR NK cells) to target and calm overactive immune cells that attack the kidneys. It is for people with active lupus nephritis or primary membranous nephropathy who have not responded to standard treatments. The main goal is to check safety, but researchers will also look for signs of kidney improvement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nkarta Investigational Site

    RECRUITING

    Little Rock, Arkansas, 72201, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Tustin, California, 92780, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact

  • Nkarta Investigational Site

    WITHDRAWN

    Miami, Florida, 33133, United States

  • Nkarta Investigational Site

    RECRUITING

    Plantation, Florida, 33317, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Tampa, Florida, 33602, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Atlanta, Georgia, 30303, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    New Orleans, Louisiana, 70112, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Worcester, Massachusetts, 01608, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Summit, New Jersey, 07901, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    New York, New York, 10007, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Syracuse, New York, 13202, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Dallas, Texas, 75201, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Houston, Texas, 77002, United States

    Contact

  • Nkarta Investigational Site

    RECRUITING

    Manati, 00674, Puerto Rico

    Contact

Conditions

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