Immune cells injected into brain tumors: a new hope for kids?
NCT ID NCT05887882
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-phase trial tests whether natural killer (NK) cells from healthy donors can be safely injected into the brain tumors of children and young adults whose cancer has returned or is growing. The NK cells are specially treated to resist the tumor's defenses. The main goals are to find the safest dose and check for side effects. The study is currently on hold.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
natural killer cells from healthy donors
What this could lead to
If it works, this could point toward a new treatment option for children and young adults with hard-to-treat brain tumors.
What could go wrong
This is a very early phase I trial with only 24 participants, so safety and dosing are still being figured out. It is currently suspended, and there is no guarantee it will lead to an effective treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Indiana University
Indianapolis, Indiana, 46202, United States
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Johns Hopkins
Baltimore, Maryland, 21287, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Seattle Children's
Seattle, Washington, 98105, United States
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The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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University of Alabama Birmingham
Birmingham, Alabama, 35294, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
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Washington University in Saint Louis
St Louis, Missouri, 63130, United States