New combo shows promise for tough cancers

NCT ID NCT03728361

First seen Jan 04, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This study tests a combination of two drugs—nivolumab (an immunotherapy that helps the immune system fight cancer) and temozolomide (a chemotherapy drug)—in people with small-cell lung cancer that has returned or stopped responding to treatment, or advanced neuroendocrine tumors. About 55 participants will receive both drugs to see if the combination can shrink tumors. The goal is to find a better option for these hard-to-treat cancers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center-COHORT 1

    Columbus, Ohio, 43210, United States

  • Ohio State University Comprehensive Cancer Center-COHORT 2

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.