New combo therapy tested for Tough-to-Treat cancers that have returned

NCT ID NCT03728361

Summary

This study is testing whether combining two existing drugs—nivolumab (an immunotherapy) and temozolomide (a chemotherapy)—can help control cancers that have come back or stopped responding to standard treatments. It is for adults with recurrent small-cell lung cancer or advanced neuroendocrine tumors that have spread. The main goal is to see if this combination can shrink tumors and for how long it can keep the cancer from getting worse.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center-COHORT 1

    Columbus, Ohio, 43210, United States

  • Ohio State University Comprehensive Cancer Center-COHORT 2

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.