Immunotherapy combo shows promise in shrinking oral tumors before surgery

NCT ID NCT02919683

First seen Feb 01, 2026 · Last updated May 11, 2026 · Updated 11 times

Summary

This study tested two immunotherapy drugs, nivolumab and ipilimumab, given before surgery to people with oral cavity squamous cell carcinoma. The goal was to see if the drugs could shrink tumors and be safe. 30 adults with stage T2 or higher tumors took part. The approach aims to improve outcomes by using the body's immune system to fight cancer before surgical removal.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

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