Immunotherapy duo targets Hard-to-Treat breast cancer

NCT ID NCT03789110

First seen Feb 06, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study tests whether combining two immunotherapy drugs, nivolumab and ipilimumab, can shrink tumors in people with a rare, hard-to-treat form of advanced breast cancer that has many genetic mutations. The study enrolled 30 adults with HER2-negative breast cancer that has spread. The goal is to see how many patients respond to the treatment.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.