Triple therapy aims to control hard-to-treat bone marrow cancer

NCT ID NCT02530463

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 23 times

Summary

This study tests whether combining two immunotherapy drugs (nivolumab and ipilimumab) with a chemotherapy drug (azacitidine) can help people with myelodysplastic syndromes (MDS), a bone marrow disorder. About 99 adults with MDS, including those who have not responded to prior treatments, are taking part. The goal is to see if the combination improves response rates, such as reducing cancer cells or improving blood counts.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.