Immunotherapy drug nivolumab takes on rare childhood cancer

NCT ID NCT06622941

First seen Feb 04, 2026 · Last updated Jun 23, 2026 · Updated 18 times

Summary

This phase 2 trial is testing the immunotherapy drug nivolumab in 23 people aged 1 year and older with advanced or recurrent rhabdoid tumors that have not responded to chemotherapy. The goal is to see if the drug can shrink tumors and improve survival. Participants receive nivolumab every two weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hokkaido University Hospital

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hyogo Prefectural Kobe Children's Hospital

    RECRUITING

    Kobe, Hyōgo, Japan

  • Nagoya University Hospital

    RECRUITING

    Nagoya, Aichi-ken, Japan

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, Japan

  • Osaka City General Hospital

    RECRUITING

    Osaka, Osaka, Japan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nivolumab (a type of immunotherapy that helps the immune system fight cancer)

What this could lead to

If it works, this could offer a new treatment option for people with rhabdoid tumors that have not responded to chemotherapy.

What could go wrong

This is a small, early-phase trial with only 23 participants, so results may not apply to everyone. Immunotherapy can cause side effects like inflammation in healthy organs.

Conditions

The condition(s) this trial relates to.

rhabdoid tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.