Immunotherapy combo shows promise against returning bone cancer
NCT ID NCT03628209
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 30 times
Summary
This study tests two treatments—nivolumab alone or with azacitidine—in people whose osteosarcoma (a type of bone cancer) has come back and can be surgically removed. The goal is to see if these drugs are safe and help keep the cancer from returning after surgery. About 21 adults and children with cancer only in the lungs are taking part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred I DuPont Hospital for Children
Wilmington, Delaware, 19803, United States
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Carolina Medical Center, Levine Cancer Institute
Charlotte, North Carolina, 28203, United States
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Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Los Angeles, USC Norris Comprehensive Cancer Center
Los Angeles, California, 90027, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Connecticut Children's Medical Center
Hartford, Connecticut, 06106, United States
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Duke Health
Durham, North Carolina, 27708, United States
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H. Lee Moffitt Cancer Center and Research Institute, Coordinating Center
Tampa, Florida, 33612, United States
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Johns Hopkins All Children's Hospital
St. Petersburg, Florida, 33701, United States
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Johns Hopkins University, Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Nemours Children's Clinic
Orlando, Florida, 32806, United States
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Nemours Children's Hospital
Jacksonville, Florida, 32207, United States
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14203, United States
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Shand's Hospital for Children at the University of Florida
Gainesville, Florida, 32610, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Kentucky, Markey Cancer Center
Lexington, Kentucky, 40536, United States
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University of Miami - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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University of Texas M.D. Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
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