Triple therapy shows promise for tough brain tumor

NCT ID NCT03743662

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study tests whether adding the immunotherapy drug nivolumab to radiation and another drug called bevacizumab can help people with a returning type of brain cancer called glioblastoma. The trial includes 39 adults whose tumors have a specific genetic marker (MGMT methylated) and have already received standard treatment. The goal is to see if this combination improves survival and controls the cancer longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hartford Healthcare (Data Collection)

    Hartford, Connecticut, 06102, United States

  • Indiana University (Data Collection Only)

    Indianapolis, Indiana, 46202, United States

  • Lehigh Valley Health Network (Data Collection Only)

    Allentown, Pennsylvania, 18103, United States

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

  • University of Vermont Medical Center (Data Collection Only)

    Burlington, Vermont, 05401, United States

Conditions

Explore the condition pages connected to this study.