Ovarian cancer: can a second round of niraparib after surgery keep tumors at bay?

NCT ID NCT06180356

Recruiting now Disease control Sponsor: MedSIR Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether giving the drug niraparib again after surgery can help women with ovarian cancer whose disease has come back in just a few spots. About 30 participants will take niraparib pills daily until their cancer grows or side effects become too much. The main goal is to see how long they live without their cancer getting worse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: niraparib (a PARP inhibitor oral tablet)
What this could lead to: If successful, this could offer a new treatment option for ovarian cancer patients whose disease has come back in a few spots after initial therapy.
What could go wrong: This is a small, early-phase study with only 30 patients. It may not show a clear benefit, and side effects from niraparib (like low blood counts) are possible.

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Conditions

The condition(s) this trial relates to.

ovarian cancer ovarian endometrioid adenocarcinoma ovarian serous adenocarcinoma ovarian serous tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OLIGOMETASTATIC DISEASE OVARIAN CANCER SEROUS OVARIAN TUMOR

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Complejo Hospitalario Universitario A Coruña (CHUAC)
RECRUITING

A Coruña, Spain
Complejo Hospitalario de Jaén
RECRUITING

Jaén, Spain
Hospital Arnau de Vilanova de Valencia
RECRUITING

Valencia, Spain
Hospital Universitari Sant Joan de Reus
RECRUITING

Tarragona, Spain
Hospital Universitari Vall D'Hebron
RECRUITING

Barcelona, Spain
Hospital Universitari i Politècnic La Fe
RECRUITING

Valencia, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Spain
Hospital Universitario Central de Asturias (HUCA)
RECRUITING

Oviedo, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, Spain
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, Spain
Hospital de Cruces
RECRUITING

Barakaldo, Spain
Institut Català d' Oncologia Girona (ICO)
RECRUITING

Girona, Spain

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